Microbiology Major

Course Listings

Agriculture and Environmental Science 015

11:015:101 Perspectives on Agriculture and the Environment (2)
Examines several current issues to introduce the land-grant mission of the college and the multidisciplinary nature of both the problems and solutions it addresses.
Lec./rec. 3 hrs. for the first 10 weeks of fall term. For entering first-year and transfer students with 36 credits or less.

11:015:405 Ethics in Science Brief Description of this Colloquium
Exploration of a variety of ethical issues related to science, including, but not limited to gene patents, conflict of interest, insider trading, cures of disease, endangered species, human experimentation, and man and the environment. Students work in small groups on a particular issue of their choosing.

11:015:433 Critical Thinking in Science
Exploration of the critical thinking necessary for scientific investigation and for the evaluation of scientific and technical information. The course will focus on understanding the research process, the developmental stages of a research project, data evaluation, and research publications. The class will explore the intellectual road from observation, empiricism, hypothesis, data gathering, and analysis to conclusions. Case studies, using real world examples and practical applications will illustrate critical thinking and the impact of science and technology on society. Participants in the Colloquium will integrate research information from a variety of fields, such as earth system science, environmental sciences, chemistry, biology, ecology, biochemistry, medicine, social sciences, public policy and economics.

Biology (Life Sciences) 119 FAS

01:119:101-102 General Biology (4,4)
Broad principles of cell biology, genetics, and evolution; physiology, ecology, and population dynamics of plant and animal systems. Lec./rec. 3 hrs., lab. 3 hrs. Pre- or corequisites: 01: 350:101; 01:640:111-112, or 115. Designed for science majors.

01:119:160 Biology, Society, and Ecological Issues (3)
Ecological and evolutionary ideas affecting space ecology; population increase, food supply, air and water pollution, war, and nuclear energy. Not open to students in a life sciences or related major

Biochemistry 115

11:115:403,404 General Biochemistry (4,3)
A comprehensive survey of the chemistry and metabolism of biological compounds, including proteins, polysaccharides, lipids, and nucleic acids. Enzyme kinetics, bioenergetics, organelles, and cellular organization. Expression and processing of biological information, including DNA replication; transcription into RNA; translation into protein, regulation, and recombinant DNA techniques. Computer modeling of macromolecules. Prerequisites: 01:160:307-308 or 315-316 with grades of C or better.

11:115:412 Protein and Enzyme Chemistry (3)
Assay and purification of enzymes and other proteins. Chemical modification, site-directed mutagenesis, and enzyme kinetics as tools in understanding structure-function relationships and enzyme mechanisms. Mechanisms of selected enzymes. Prerequisites: 11:115:403, 413, or equivalents.

11:115:413,414 Experimental Biochemistry (3,2.5)
Isolation, characterization, and quantitative determination of biological compounds. Spectrophotometric and titrimetric analyses; chromatography and gel electrophoresis; high performance liquid chromatography. Isolation and characterization of enzymes, nucleic acids, and lipids. Graphing and statistical treatment using computers. Lec. 1 hr., lab. 4.5 hrs. Corequisites: 11:115: 403,404. Recommended: 01:447:380.

11:115:428 Homology Modeling of Proteins (3)
Computer construction of models of the three-dimensional structure of proteins, based on known structures of proteins with related sequences. Interpretation and prediction of function based on the modeled structure. Prerequisite: 11:115:403.

Biotechnology 126

11:126:405 Microbial Technology (3)
An integrated discussion of recent genetic, biochemical, and engineering approaches to microbial processing, from antibiotics, biomass, and citric acid to Zymomonas.
Prerequisites: 11:680:390, 11:680:394 or 11:126:394 or 11:126:491 or 11:680:491.

11:126:407Comparative Virology (3)
Biology of viruses and approaches to control through antivirals and genetic engineering. Genome organization, gene expression, replication, movement, and transmission across kingdoms. Prerequisites: 01:119:101-102, organic chemistry.

11:126:410 Process Biotechnology (3)
Survey of the applications of biotechnology, emphasizing the pharmaceutical industry and the operation of fermentation systems. Case studies of downstream separation and purification protocols employed on an industrial scale. Prerequisites: 01:447:390, one term of biochemistry.

11:126:413 Plant Molecular Biology (3)
Fundamental and applied aspects of plant molecular biology: structure, expression, and isolation of plant nuclear genes; molecular biology of plant development, plant organelles, and plant- microbe interactions; and plant biotechnology.
Prerequisites: 01:447:380, 01:447:482/11:126:481 or 11: 115:404 or 01:694:408.

11:126:427 Methods in Recombinant DNA Technology (4)
Introduction to techniques and experimental approaches used in recombinant DNA technology. One 80-min. lec., one 55-min. rec., one 300-min. lab. Prerequisites: 01:447:380, 11:126:481, 482.

11:126:482 Molecular Genetics Laboratory (3)
Biochemical and molecular aspects of gene function and gene recombination.
One 240-min. lab., one 80-min. lab., one 55-min. lec. Credit not given for both this course and 01:447:483 or 01:119:483. Prerequisites: 11:126:481 and 11:680:390.

11:126:483 Nucleotide Sequence Analysis (3)
Computer analysis of nucleotide sequences: assembly; restriction analysis; gene location and identification; protein sequence analysis and structure prediction; database searching; sequence alignments; and phylogenetic analysis.
Prerequisites: 11:115:403, 404 or 01:447:482/11:126: 481 or 427.

11:126:484 Biotechnology Robotics (3)
Application and use of robotic equipment in the analysis of large numbers of samples; assay and protocol design; data collating, analysis and interpretation; applications in various life science industries. One 80-min. lec., 4.5 hrs. lab. Prerequisites: 11:115: 403, 11:115:313 or 413, 11:680:390.

11:126:486 Analytical Methods in Microbiology (4)
Hands-on training in the use of analytical instrumentation in microbiological research and applications, including biotransformations and fermentations, biodegredation, and identification of bacteria and fungi. One 80-min. lec., one 4.5-hr. lab., one 80-min. rec. Prerequisites: 11:126:394 or 11:680:394, 11:680:390.

Bioresource Engineering 127

11:127:414 Unit Processes in Bioenvironmental Engineering II (3)
Biological principles and operations, including microbial ecology, stoichiometry and kinetics of organic contaminant degradation and biomass growth, modeling of ideal biochemical reactors, design criteria for several named biochemical operations used for wastewater treatment. Prerequisites: 01:447:390, 11:127:413, or permission of instructor.

Cell Biology and Neuroscience 146 (FAS)

01:146:328 Human Parasitology (3)
Discussion of the cell biology, epidemiology, pathogenesis, and clinical manifestations of human parasitic diseases. (Formerly 01:119:328) Lec. 3 hrs. Prerequisites: 01:119:101,102. Credit not given for both this course and 01:146:327.

01:146:474 Immunology (3)
Fundamental principles of immunology with emphasis on antibody formation, immunoglobulin molecules and genes, hypersensitivity reactions, and the cellular basis for the immune response. (Formerly 01:119:474) Prerequisites: 01:119:101-102 and 01:447:380. Recommended: 01:447:390.

01:146:475 Laboratory in Immunology (1)
Biochemical and molecular analysis of immune cell function. Application of immunological techniques to the examination of normal and diseased states.
Pre- or corequisite: 01:146:474.

Chemistry 160 (FAS)

01:160:161-162 General Chemistry (4,4)
Introduction to chemical principles and their application. Topics include stoichiometry, states of matter, atomic and molecular structure, solutions, thermodynamics, equilibrium, oxidation- reduction, kinetics, nonmetals, metals and coordination compounds, and nuclear chemistry. Lec. 3 hrs., rec. 1 hr. Pre- or corequisite for 161:01: 640:111 or 01:640:115 or equivalent. Pre- or corequisite for 162:01:160: 171. Prerequisite for 162:01:640:111 or 01:640:115 or equivalent. For science majors. Credit not given for both these courses and 01:160: 163-164.

01:160:171 Introduction to Experimentation (1) Laboratory illustrating basic chemical methods. Lab. fee: $25. Lab. 3 hrs. Pre- or corequisite: 01:160:159, 161, or 163

01:160:307-308Organic Chemistry (4,4)
Develops proficiency in preparation and manipulation. Chromatographic and spectroscopic techniques applied to solutions of problems. Qualitative organic analysis.
Lec. 1 hr., lab. 4.5 hrs. Prerequisites: 01:160:171 and 307.

Environmental Sciences 375

11:375:312 Environmental Microbiology Laboratory (2)
Hands-on introduction to microbiological techniques related to environmental issues. Bacterial growth and nutrition, nutrient cycles, waste treatment, and water quality testing. Pre- or corequisites: 11:375:201, 202.

11:375:411 Enviromental (Pollution) Microbiology (3)
Microorganisms as polluters and purifiers of the environment. Biological cycling of carbon, nitrogen, and other elements; sewage and solid waste treatment; sanitary bacteriology. Prerequisite: One term of introductory microbiology or bacteriology.

11:375:453Soil Ecology (3)
Soil microbial contribution to ecosystem function, microbial diversity, nutrient cycling, soil enzymes, fate of soil amend- ments, soil flora and fauna, energy cycling, quantification of soil biological processes. Prerequisite: 11:375:266 or permission of instructor.

Food Science 400

11:400:423 Food Microbiology (3)
The role of microorganisms in food processing and preserva- tion and health promotion. The relation of microorganisms to food spoilage, food borne illness and intoxication, and general food quality. Prerequisite: 01:447:390. 11:115:301 or 403 recommended.

11:400:424 Food Microbiology Laboratory (1)
Methods of microbiological analysis of foods. Identification of food-related microorganisms and fermentation processes. Corequisite: 11:400:423.

Genetics 447 FAS

01:447:380 Genetics (4)
Introduction to the mechanisms of heredity and evolution. Mechanisms of Mendelian inheritance, meiosis, recombination, gene mutation, and mapping. An introduction to modern biochemical, molecular, and population genetics. Lec. 3 hrs., rec. 1 hr. Prerequisites: 01:119:101-102 and 01:160:161-162, 171. Credit not given for both this course and 01:447: 384-385, or 11:067:328 or 11:776:305.

01:447:398 Electron Microscopy (4)
Theory, practice, and application of transmission electron microscopy and scanning electron microscopy; emphasis on material relevant to genetics.
Pre- or corequisites: 01:119:102, 01:750:203-204; permission of instructor (limited enrollment).

01:447:480 Topics in Molecular Genetics (3)
Current research topics in microbial and molecular genetics. Lectures, discussions, and critical analysis of journal articles. Prerequisite: 01:447:380.

Marine Sciences 628

11:628:404 Fungi and Ecosystems (3)
Ecophysiology of fungi and their role in the processes of decomposition, pathogenicity, and plant nutrient acquisition. Growth habit, colonization ability, resource availability and requirements, and community structure in terrestrial, aquatic, and marine ecosystems. Prerequisites: 01:119:101-102. Recommended: 01:447: 390, 11:375:453,

11:628:418 Marine Microbiology (4)
Survey of marine bacteria with emphasis on biochemical adap-tations to the ocean realm. Biogeochemical cycling, marine bioremediation, molecular ecology, and vent symbioses. Laboratory characterization of marine samples using recombinant DNA techniques. Two 80-min. lecs., lab. 3 hrs. Prerequisite: Permission of instructor.

Microbiology 680

11:680:390 General Microbiology (4)
Basic principles of microbiology. An introduction to the physiology, morphology, pathogenicity, and genetics of groups of microorganisms.
Lec. 3 hrs., lab. 3 hrs. Prerequisites: 01:119: 101-102; 01:160:161-162, 171, and 307.

11:680:394 Applied Microbiology (4) Microorganisms in foods; their application in industry, agriculture, environment, and medicine. Physical and chemical factors of growth and control in relation to industrial and natural processes.
Lec. 3 hrs., lab. 3 hrs. Prerequisite: 11:680:390 or equivalent. Credit not given for both this course and 11:126:394.

11:680:401 Ethics and Issues in Microbiology (1)
Ethical and current issues in microbiology are discussed from the perspective of scientific and ethical conduct. Case studies will be analyzed. The course is targeted for students in their junior/senior year majoring microbiology and provides a fundamental understanding of a code of ethics for microbiologists, including ethical conduct, scientific integrity and the dignity of the profession and practice of microbiology.

11:680:491 Microbial Ecology and Diversity (3)
Ecological determinants; characteristics of aquatic and terrestrial ecosystems; nature and activity of microbial populations; biogeochemical cycles and energy flow; microbial interactions and community structures. Two 80-min. lecs., Prerequisite: 01: 447:390 or 11:680:390.

11:680:492 Microbial Ecology and Diversity Lab (1)

11:680:495 Seminar in Microbiology (1)
Practice in techniques for oral presentation of scientific reports and reviews, based on search of research literature in microbiology and, where applicable, the student's own research results. Open only to senior microbiology majors.

11:680: 497,498 Research in Microbiology (BA,BA)
Research projects in microbiology under the guidance of faculty members.
Prerequisite: Permission of instructor

Natural Resource Management 704

11:704:422 Ecology of Soil Organisms (3)
Diversity of organisms and complexity of communities in below-ground ecosystems. Range and diversity of soil organisms and their role in the development of soils, soil structure, soil fertility, and ecosystem processes. Prerequisites: 01:119:101-102.

Plant Pathology 770

11:770:301 General Plant Pathology (3)
The occurrence, economic importance, symptoms, causes, and control of plant diseases.
Prerequisites: 01:119:101-102.

Physics 750 FAS

01:750:193-194 Physics for the Sciences (4,4) Introduction to physics with biological, ecological, and chemical applications. Selected topics in mechanics, thermodynamics, fluids, waves, electricity, magnetism, optics, and modern physics. Integrated laboratory experiments. Lec. 2 hrs., workshop 1.5 hrs., lab. 3 hrs. Prerequisite: 01:640:112 or 115 or equivalent